Anti-Aging & Biological Rejuvenation

Biological rejuvenation is not a one-time treatment — it is a structured, phased program. Most patients undergo an initial intensive phase of 3–4 months with weekly or bi-weekly interventions (NAD+ IVs, peptide therapy, nutritional optimization), followed by a maintenance phase of monthly or quarterly sessions. Measurable biological changes in epigenetic age, mitochondrial function, and inflammatory markers typically begin appearing within 8–12 weeks, with cumulative benefits over 6–12 months. Long-term patients often transition to an optimization phase that preserves gains.

Yes — when administered under clinical supervision by a qualified medical professional. At BioReset, all IV and peptide therapies are prescribed only after comprehensive laboratory assessment and medical history review. NAD+ IVs are administered at controlled rates with nursing oversight. Peptide therapies such as GHK-Cu and BPC-157 are sourced from certified compounding pharmacies and dosed individually. Side effects are rare and typically mild (e.g., transient flushing with NAD+). All protocols include ongoing monitoring of liver function, kidney function, and metabolic markers to ensure safety throughout the program.

Most patients report subjective improvements — increased energy, better sleep quality, enhanced mental clarity, improved skin texture — within the first 4–6 weeks of the intensive phase. Objective biological markers (epigenetic clock reversal, NAD+ level restoration, inflammatory marker reduction, mitochondrial ATP output) are typically re-measured at the 3-month and 6-month marks, with progressive improvement documented across the program. Individual timelines vary based on baseline biological age, the severity of cellular dysfunction, and adherence to the full protocol including nutrition, sleep, and movement recommendations.

Absolutely — and in many cases, this is the optimal approach. Patients with chronic fatigue, Lyme disease, or detoxification needs often find that addressing biological aging accelerates their overall recovery. Conversely, patients primarily seeking rejuvenation may benefit from concurrent microbiome restoration, detoxification, or mitochondrial support. Dr. Milios designs integrated protocols where anti-aging interventions are sequenced and combined with other biological restoration treatments for maximum synergistic effect.

We track a comprehensive panel of aging biomarkers: epigenetic clock (biological vs. chronological age), NAD+ and NADH levels, mitochondrial ATP production capacity, inflammatory markers (CRP, IL-6, TNF-alpha), oxidative stress indices (GSH/GSSG ratio, lipid peroxidation), hormonal panels (thyroid, adrenal, sex hormones), telomere length analysis, and metabolic flexibility markers (HbA1c, fasting insulin, lipid profiles). These are measured at baseline, 3 months, 6 months, and 12 months to document objective biological change.